Total synthesis of (-)- and (+)-tedanalactam

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dc.contributor.author Majik, M.S.
dc.contributor.author Parameswaran, P.S.
dc.contributor.author Tilve, S.G.
dc.date.accessioned 2009-12-18T09:04:24Z
dc.date.available 2009-12-18T09:04:24Z
dc.date.issued 2009
dc.identifier.citation The Journal of Organic Chemistry, vol.74(16); 6378-6381
dc.identifier.uri http://drs.nio.org/drs/handle/2264/3477
dc.description.abstract The first stereoselective route providing access to both enantiomers of tedanalactam, a naturally occurring piperidone, has been developed. The stereogenic centers were generated by the use of Sharpless asymmetric dihydroxylation. Tandem oxidation-Wittig reaction and one-pot deprotection, lactamization, and oxirane ring formation are the other key elements
dc.language.iso en
dc.publisher American Chemical Society
dc.rights Copyright ACS [2009]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subject tedanalactam
dc.subject enantiomers
dc.subject piperidone
dc.subject oxidation-Wittig reaction
dc.title Total synthesis of (-)- and (+)-tedanalactam
dc.type Journal Article


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