Marine metabolites: The sterols of soft coral

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dc.contributor.author Sarma, N.S.
dc.contributor.author Krishna, M.S.
dc.contributor.author Pasha, Sk.G.
dc.contributor.author Rao, T.S.P.
dc.contributor.author Venkateswarlu, Y.
dc.contributor.author Parameswaran, P.S.
dc.date.accessioned 2009-12-21T06:45:22Z
dc.date.available 2009-12-21T06:45:22Z
dc.date.issued 2009
dc.identifier.citation Chemical Reviews, vol.109(6); 2803-2828
dc.identifier.uri http://drs.nio.org/drs/handle/2264/3490
dc.description.abstract Sterols constitute a major group of secondary metabolites of soft corals. Several of these compounds have the 'usual' 3 beta-hydroxy, delta sup(5) (or delta sup(0)) cholestane skeleton, a large number of these metabolites are polar sterols with multiple oxygenations in rings as well as side chains. The latter compounds are structurally similar to some of the steroidal hormones, bile acids, signaling agents, etc., with potential therapeutic applications in the fields of cancer, atherosclerosis, and other diseases. The present review lists 561 structurally diverse sterols of marine soft coral origin and attempts to codify their structural types. This will help in chemotaxonomic investigations of these organisms and stimulate biochemists to look for useful enzymes for conversion of normal sterols into biologically useful derivatives.
dc.language.iso en
dc.publisher American Chemical Society
dc.rights © 2009 American Chemical Society. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subject marine invertebrates
dc.subject chemical extraction
dc.subject metabolites
dc.subject coral
dc.title Marine metabolites: The sterols of soft coral
dc.type Journal Article


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