dc.contributor.author | Parsekar, S.B. | |
dc.contributor.author | Amonkar, C.P. | |
dc.contributor.author | Parameswaran, P.S. | |
dc.contributor.author | Tilve, S.G. | |
dc.date.accessioned | 2010-11-29T06:43:56Z | |
dc.date.available | 2010-11-29T06:43:56Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Synthetic Communications, vol.40(21); 3251-3258 | |
dc.identifier.uri | http://drs.nio.org/drs/handle/2264/3739 | |
dc.description.abstract | A convenient general synthesis of 2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]quinolines using the Wittig reaction is described. The o-nitrobenzaldehydes (1a-d) on reaction with phosphorane 2 provided (E)-ethyl-a-(2,2-dimethylprop-2-ene)-2-nitrocinnamates (3a-d) in excellent yields, which on cyclization with polyphosphoric acid followed by reductive cyclization using Fe/HCl afforded dihydropyranoquinolines (5a-d). Alternatively, the pyranoquinolines 5a-d were also synthesised from esters 3a-d by employing domino reductive cyclization in a single step | |
dc.language.iso | en | |
dc.publisher | Taylor & Francis | |
dc.rights | The final and definitive form of the preprint has been published in the "Synthetic Communications" © 2010 Taylor & Francis; "Synthetic Communications" is available online at http://www.informaworld.com/ with open URL of artilce : http://www.informaworld.com/smpp/content~db=all?content=10.1080/00397910903398668 | |
dc.subject | chemical extraction | |
dc.subject | Balfourodendron riedelianum | |
dc.subject | alkaloids | |
dc.subject | Wittig reaction | |
dc.title | Convenient synthesis of 2,2-Dimethyl-3,4-dihydro-2 H-pyrano[2,3- b]quinolines | |
dc.type | Journal Article | |