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dc.contributor.authorParsekar, S.B.
dc.contributor.authorAmonkar, C.P.
dc.contributor.authorParameswaran, P.S.
dc.contributor.authorTilve, S.G.
dc.date.accessioned2010-11-29T06:43:56Z
dc.date.available2010-11-29T06:43:56Z
dc.date.issued2010
dc.identifier.citationSynthetic Communications, vol.40(21); 3251-3258
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/3739
dc.description.abstractA convenient general synthesis of 2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]quinolines using the Wittig reaction is described. The o-nitrobenzaldehydes (1a-d) on reaction with phosphorane 2 provided (E)-ethyl-a-(2,2-dimethylprop-2-ene)-2-nitrocinnamates (3a-d) in excellent yields, which on cyclization with polyphosphoric acid followed by reductive cyclization using Fe/HCl afforded dihydropyranoquinolines (5a-d). Alternatively, the pyranoquinolines 5a-d were also synthesised from esters 3a-d by employing domino reductive cyclization in a single step
dc.language.isoen
dc.publisherTaylor & Francis
dc.rightsThe final and definitive form of the preprint has been published in the "Synthetic Communications" © 2010 Taylor & Francis; "Synthetic Communications" is available online at http://www.informaworld.com/ with open URL of artilce : http://www.informaworld.com/smpp/content~db=all?content=10.1080/00397910903398668
dc.subjectchemical extraction
dc.subjectBalfourodendron riedelianum
dc.subjectalkaloids
dc.subjectWittig reaction
dc.titleConvenient synthesis of 2,2-Dimethyl-3,4-dihydro-2 H-pyrano[2,3- b]quinolines
dc.typeJournal Article


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