A role for antioxidants in acclimation of marine derived pathogenic fungus (NIOCC 1) to salt stress

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dc.contributor.author Ravindran, C.
dc.contributor.author Varatharajan, G.R.
dc.contributor.author Rajasabapathy, R.
dc.contributor.author Vijayakanth, S.
dc.contributor.author HarishKumar, A.
dc.contributor.author Meena, R.M.
dc.date.accessioned 2012-08-21T06:07:00Z
dc.date.available 2012-08-21T06:07:00Z
dc.date.issued 2012
dc.identifier.citation Microbial Pathogenesis, vol.53; 2012; 168-179
dc.identifier.other no
dc.identifier.uri http://drs.nio.org/drs/handle/2264/4118
dc.description.abstract Salinity tolerance a key factor helps in understanding the ionic homeostasis in general is a fundamental cellular phenomenon in all living cells. A marine derived pathogenic fungus was examined for its adaptation under salt stress using antioxidant properties. The aqueous extracts of halophilic fungus exhibited different levels of antioxidant activity in all the in vitro tests such as alpha, alpha-diphenyl-beta-picrylhydrazyl (DPPH'), Hydroxyl Radical Scavenging Assay (HRSA), Metal chelating assay and beta-carotene-linoleic acid model system. The antioxidant capacity of marine fungus exposed to high salt condition showed an increase in activity. In addition, the production of intra and extracellular antioxidant enzymes of the fungus at various salt stresses were analyzed and discussed for their possible role in the stress mechanism. The marine derived fungus was identified as Phialosimplex genus, which is associated with infections in dogs. Thus the present study elucidates that the scavenging activity is one of the protective mechanisms developed in the fungus to avoid the deleterious effect of salt stress. In addition, the study also helps in understanding how the pathogenic fungus tackles the oxidative burst i.e. hypersensitivity reaction performed by host to kill the pathogens.
dc.language.iso en
dc.publisher Elsevier
dc.relation.requires Microb_Pathogenesis_53_168.jpg
dc.rights An edited version of this paper was published by Elsevier. Copyright [2012] Elsevier
dc.subject fungi
dc.subject pathogens
dc.subject antioxidants
dc.title A role for antioxidants in acclimation of marine derived pathogenic fungus (NIOCC 1) to salt stress
dc.type Journal Article


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