Recent advances in marine drug research
Abstract
Structures and properties of promising marine anti-cancer, anti-inflammation and anti-infectious (HIV, HSV, malaria, leishmania) compounds reported during 2008–2011 are discussed. Wherever possible, attempts have also been made to highlight their possible biogenesis or structure–activity relationships (SAR). Since the stress is on identifying and short-listing potential drug molecules, this review is restricted to only those compounds exhibiting promising in vitro activity, the arbitrary cut off being IC<sub>50</sub> < 15 ~kM, reported during the above period.
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