dc.contributor.author | Ciavatta, M.L. | |
dc.contributor.author | PrabhaDevi | |
dc.contributor.author | Carbone, M. | |
dc.contributor.author | Mathieu, V. | |
dc.contributor.author | Kiss, R. | |
dc.contributor.author | Casapullo, A. | |
dc.contributor.author | Gavagnin, M. | |
dc.date.accessioned | 2016-02-04T04:47:09Z | |
dc.date.available | 2016-02-04T04:47:09Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Tetrahedron, vol.72; 2016; 625-631 | |
dc.identifier.uri | http://drs.nio.org/drs/handle/2264/4902 | |
dc.description.abstract | Bioassay-guided fractionation of the CHCl<sub>3</sub>/MeOH extract of Elysia ornata mucus showing antifungal activity led us to isolate kahalalide F(KF) along with two unprecedented related peptides. The structures of kahalalide Z<sub>2</sub>(1) and kahalalide Z<sub>2</sub>(2), were established by combination of NMR spectroscopic and mass spectrometry data, also including Marfey amino acid analysis. Compounds 1 and 2 displayed significant antimicrobial properties against several fungal pathogens infesting economically important plants, food, and fish, and were also found to inhibit the in vitro growth of a series of cancer cell lines in a comparable fashion with KF | |
dc.language.iso | en | |
dc.publisher | Elsevier | |
dc.rights | An edited version of this paper was published by Elsevier. Copyright [2015] Elsevier | |
dc.subject | MOLLUSCS | |
dc.subject | AQUATIC RESOURCES | |
dc.title | Kahalalide F analogues from the mucous secretion of Indian sacoglossan mollusc Elysia ornata | |
dc.type | Journal Article | |