Show simple item record

dc.contributor.authorCiavatta, M.L.
dc.contributor.authorPrabhaDevi
dc.contributor.authorCarbone, M.
dc.contributor.authorMathieu, V.
dc.contributor.authorKiss, R.
dc.contributor.authorCasapullo, A.
dc.contributor.authorGavagnin, M.
dc.date.accessioned2016-02-04T04:47:09Z
dc.date.available2016-02-04T04:47:09Z
dc.date.issued2016
dc.identifier.citationTetrahedron, vol.72; 2016; 625-631
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/4902
dc.description.abstractBioassay-guided fractionation of the CHCl<sub>3</sub>/MeOH extract of Elysia ornata mucus showing antifungal activity led us to isolate kahalalide F(KF) along with two unprecedented related peptides. The structures of kahalalide Z<sub>2</sub>(1) and kahalalide Z<sub>2</sub>(2), were established by combination of NMR spectroscopic and mass spectrometry data, also including Marfey amino acid analysis. Compounds 1 and 2 displayed significant antimicrobial properties against several fungal pathogens infesting economically important plants, food, and fish, and were also found to inhibit the in vitro growth of a series of cancer cell lines in a comparable fashion with KF
dc.language.isoen
dc.publisherElsevier
dc.rightsAn edited version of this paper was published by Elsevier. Copyright [2015] Elsevier
dc.subjectMOLLUSCS
dc.subjectAQUATIC RESOURCES
dc.titleKahalalide F analogues from the mucous secretion of Indian sacoglossan mollusc Elysia ornata
dc.typeJournal Article


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record