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dc.contributor.authorTilvi, S.
dc.contributor.authorRodrigues, C.
dc.contributor.authorNaik, C.G.
dc.contributor.authorParameswaran, P.S.
dc.contributor.authorWahidullah, S.
dc.date.accessioned2008-07-02T04:52:34Z
dc.date.available2008-07-02T04:52:34Z
dc.date.issued2004
dc.identifier.citationTetrahedron, Vol.60; 10207-10215p.
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/1128
dc.description.abstractSeven new bromotyrosine alkaloids Purpurealidin A, B, C, D, F, G, H and the known compounds Purealidin Q, Purpurealidin E, 16-Debromoaplysamine-4 and Purpuramine I have been isolated from the marine sponge Psammaplysilla purpurea. Their structure was elucidated on the basis of detailed 1D, 2D NMR and MS spectroscopic data. Purpurealidin B, 16-Debromoaplysamine-4 and Purpuramine I exhibited in vitro antimicrobial activities against E. coli, S. aureus, and V. cholerae. In addition, Purpurealidin B and 16-Debromoaplysamine-4 were also active against Shigella flexineri and Salmonella typhi while Purealidin Q was bactericidal only against Salmonella typhi.
dc.language.isoen
dc.publisherElsevier
dc.rightsCopyright [2004]. It is tried to respect the rights of the copyright holders to the best of the knowledge. If it is brought to our notice that the rights are violated then the item would be withdrawn.
dc.subjectmarine invertebrats
dc.subjectbioactive compounds
dc.subjectalkaloids
dc.subjectchemical extraction
dc.subjectPsammaplysilla purpurea
dc.titleNew bromotyrosine alkaloids from the marine sponge Psammaplysilla purpurea
dc.typeJournal Article


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